Personalizing the Treatment of Recurrent/Metastatic HNSCC: A Multifactorial Path

Personalizing the Treatment of Recurrent/Metastatic HNSCC: A Multifactorial Path

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A paradigm shift in the frontline approach to managing recurrent/metastatic head and neck squamous cell carcinoma is underway. How prepared are you?

Available credits: 0.25

Time to complete: 15 minutes


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  • Overview

    KEYNOTE-048 has opened new vistas to managing patients with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC). Nonetheless, uncertainties remain in matching the correct patient with the correct strategy. Join Drs. Barbara Burtness and Nabil Saba as they parse the key trials and offer insight into building treatment algorithms designed to optimize outcomes for your patients with R/M HNSCC.

  • Disclosure of Conflicts of Interest

    In accordance with the ACCME Standards for Integrity and Independence, Global Learning Collaborative (GLC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any ineligible company. GLC mitigates all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.

    Barbara Burtness, MD
    Professor of Medicine (Medical Oncology)
    Yale School of Medicine and Yale Cancer Center
    New Haven, CT

    Consulting Fees: ALX Oncology, Elsevier, EMD Serono, Genentech, Janssen, Kura, Macrogenics, Merck, UMA Education Alliance, Vaccinex
    Contracted Research: Cue BioPharma, Merck, RBN, Vaccinex
    Royalties: Up to Date

    Nabil F. Saba, MD, FACP
    Professor and Vice Chair, Hematology and Medical Oncology
    The Lynne and Howard Halpern Chair in Head and Neck Cancer Research,
    Co-Director H&N CA Multidisciplinary Program
    Winship Cancer Institute, Emory University

    No relevant relationships reported.

    Reviewers/Content Planners/Authors:

    • Jorge Bacigalupo, PSM has nothing to disclose.
    • Jennifer Brutsche has nothing to disclose.
    • Cindy Davidson has nothing to disclose.
    • Barry A. Fiedel, PhD, has nothing to disclose.
    • Amanda Hilferty has nothing to disclose.
  • Learning Objectives

    After participating in this educational activity, participants should be better able to:

    • Evaluate recent efficacy and safety data of frontline regimens for the treatment of recurrent/metastatic head and neck squamous cell cancer (R/M HNSCC) in different patient subgroups
    • Integrate evidence-based guidelines, clinical factors, and patient preferences into treatment selection for patients with R/M HNSCC
  • Target Audience

    This activity is designed to meet the educational needs of medical oncologists, pathologists, radiation oncologists and other oncology HCPs treating patients with R/M HNSCC.

  • Accreditation and Credit Designation Statements

    In support of improving patient care, Global Learning Collaborative (GLC) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.



    Global Learning Collaborative (GLC) designates this enduring activity for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Global Learning Collaborative (GLC) designates this activity for 0.25 nursing contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

  • Provider(s)/Educational Partner(s)

    Prova Education designs and executes continuing education founded on evidence-based medicine, clinical need, gap analysis, learner feedback, and more. Our mission is to serve as an inventive and relevant resource for clinical content and educational interventions across a broad spectrum of specialties. 

    Prova Education's methodology demonstrates a commitment to continuing medical education and the innovative assessment of its effects. Our goal is clear—to develop and deliver the very best education in the most impactful manner and to verify its results with progressive outcomes research. 

  • Commercial Support

    This activity is supported by an independent educational grant from Merck & Co., Inc.

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of GLC and Prova Education. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience, and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and possible contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to link to a site outside of Prova Education you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site.

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