CME: What You Need to Know About Neuromodulators

What You Need to Know About Neuromodulators

What You Need to Know About Neuromodulators

The 4 FDA-approved BoNT-A products are not interchangeable, which is why clinicians need to understand their differences and appropriate uses.

Available credits: 0.25

Time to complete: 15-minutes


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  • Overview

    Cosmetic use of botulinum neurotoxin has grown significantly over the past two decades, with four products now approved for use in the US. However, there are important differences amongst these products, and their use is not interchangeable, making it essential that clinicians understand their differences and the appropriate use of each with regard to indication, mechanism of action, and injection considerations. 

  • Disclosure of Conflicts of Interest

    In accordance with the ACCME Standards for Commercial Support, Global Learning Collaborative (GLC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. GLC resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.

    Jason D. Bloom, MD, FACS
    Adjunct Assistant Professor
    Department of Otolaryngology: Head & Neck Surgery
    University of Pennsylvania
    Philadelphia, PA
    Facial Plastic & Reconstructive Surgery
    Bloom Facial Plastic Surgery
    Bryn Mawr, PA
    Consulting Fees: Allergan, Endo Pharmaceuticals, Evolus, Galderma, Merz, Prollenium, Remedly, Revance

    Melanie D. Palm, MD, MBA, FAAD, FAACS
    Medical Director, Art of Skin, MD
    Solana Beach, CA
    Associate Clinical Professor, University of California at San Diego (UCSD)
    San Diego, CA
    Consulting Fees: Alastin, Allergan, BTL, Galderma
    Contracted Research: Alastin, Allergan, BTL, Galderma, Merz
    Ownership Interest: Revance

    Susan H. Weinkle, MD
    Associate Clinical Professor of Dermatology
    University of South Florida
    Tampa, FL
    Contracted Research: Allergan, Galderma

    Reviewers/Content Planners/Authors:

    • Sean T. Barrett has nothing to disclose.
    • Stephen Chavez has nothing to disclose.
    • Amanda Hilferty has nothing to disclose.
    • William A. Mencia, MD, FACEHP, CHCP has nothing to disclose.
    • Brian P. McDonough, MD, FAAFP has nothing to disclose.
  • Learning Objectives

    After participating in this educational activity, participants should be better able to:

    • Distinguish the four FDA-approved BoNT-As with regard to indication, mechanism of action (MOA) and injection considerations.
    • Understand how individual facial anatomy influences treatment options and administration of BoNT-As.
    • Recognize the differences among the four BoNT-As in reconstitution, storage, dosing, and units.
    • Minimize risk for AEs as well as recognize and implement appropriate treatment for AEs of BoNT-As.
  • Target Audience

    This activity is designed to meet the educational needs of dermatologists and plastic surgeons.

  • Accreditation and Credit Designation Statements

    Global Learning Collaborative is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

    Global Learning Collaborative designates this enduring material for a maximum of .25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • Provider(s)/Educational Partner(s)

    Prova Education, designs and executes continuing education founded on evidence-based medicine, clinical need, gap analysis, learner feedback, and more. Our mission is to serve as an inventive and relevant resource for clinical content and educational interventions across a broad spectrum of specialties. 

    Prova Education's methodology demonstrates a commitment to continuing medical education and the innovative assessment of its effects. Our goal is clear—to develop and deliver the very best education in the most impactful manner and to verify its results with progressive outcomes research. 

  • Commercial Support

    This activity is supported by an independent educational grant from Galderma.

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of GLC and Prova Education. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and possible contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to link to a site outside of Prova Education you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site.

    Reproduction Prohibited

    Reproduction of this material is not permitted without written permission from the copyright owner.

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