Inside the 4 Hits: Targeting APRIL to Change the Course of IgAN
Richard Lafayette, MD, FACP
Dana Rizk, MD
Hong Zhang
Suzuki Yusuke, MD, PhD
The 4-Hit Hypothesis: Foundations of IgAN Pathogenesis
APRIL Uncovered: An Upstream Driver in IgAN
Mechanism-Based Targeting: Why APRIL Matters in IgAN
IgAN SOC: Strengths and Limits
Beyond RAASi and Approved Therapies: The Unmet Needs in IgAN
Emerging Evidence: IgAN Disease-Modifying Agents
Emerging Therapies in IgAN: Who Could Benefit the Most?
Targeting Lower Proteinuria Levels: Shifting the Goalpost in IgAN
Translating Guidelines to Action in IgAN: Embracing a Simultaneous Dual-Concordant Approach
The Underestimated Consequences of Uncontrolled Gout: Renal and Cardiovascular Implications
Richard Johnson, MD
Abdul Abdellatif, MD, FASN
John K. Botson, MD, RPh
Brittany Weber, MD, PhD
Gout Beyond the Joints: What’s the Hidden Danger?
Is Gout Hiding in the Nephrology Clinic?
Is Managing Gout in the Nephrology Clinic a Challenge?
Center of the Target: Which Patients Are Most Likely to Develop Gout?
Treat or Refer: Who Is Responsible for Managing Gout?
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